DNASE2 antibody (AA 201-300)

Catalog No. ABIN6989551

Product Details anti-DNASE2 Antibody

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Binding Specificity: AA 201-300

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNASE2 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNase II

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DNASE2

Target: DNASE2 (Deoxyribonuclease II, Lysosomal (DNASE2))

Alternative Name: DNase II (DNASE2 Products)

Background:

Synonyms: Acid DNase, Deoxyribonuclease 2 alpha, Deoxyribonuclease 2, Deoxyribonuclease II alpha, Deoxyribonuclease II, Deoxyribonuclease II lysosomal, Deoxyribonuclease-2-alpha, Deoxyribonuclease2, DeoxyribonucleaseII, DNASE 2, DNASE 2A, DNase II alpha, DNase II lysosomal, DNASE2, DNASE2A, DNaseII, DNL 2, DNL, DNL2, DNS2A_HUMAN, Lysosomal DNase II, R31240 2, R31240_2.

Background: Hydrolyzes DNA under acidic conditions with a preference for double-stranded DNA. Plays a major role in the degradation of nuclear DNA in cellular apoptosis during development. Necessary for proper fetal development and for definitive erythropoiesis in fetal liver, where it degrades nuclear DNA expelled from erythroid precursor cells.

Gene ID: 1777

UniProt: O00115