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NEK6 antibody (AA 81-180)

NEK6 Reactivity: Rat ELISA, IHC (p), IF (cc), IF (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6989319
  • Target See all NEK6 Antibodies
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 81-180
    Reactivity
    • 38
    • 24
    • 19
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Rat
    Host
    • 45
    • 7
    Rabbit
    Clonality
    • 44
    • 8
    Polyclonal
    Conjugate
    • 21
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEK6 antibody is un-conjugated
    Application
    • 25
    • 19
    • 19
    • 12
    • 12
    • 8
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NEK6
    Isotype
    IgG
    Top Product
    Discover our top product NEK6 Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    NEK6 (NIMA (Never in Mitosis Gene A)-Related Kinase 6 (NEK6))
    Alternative Name
    NEK6 (NEK6 Products)
    Synonyms
    1300007C09Rik antibody, si:ch211-167p9.4 antibody, ATNEK5 antibody, MOE17.17 antibody, NIMA-RELATED KINASE5 antibody, NIMA-related kinase 5 antibody, SID6-1512 antibody, NIMA (never in mitosis gene a)-related expressed kinase 6 antibody, NIMA-related kinase 6 antibody, NIMA related kinase 6 antibody, Serine/Threonine kinase catalytic domain protein antibody, NIMA-related kinase 6 S homeolog antibody, Nek6 antibody, nek6 antibody, NEK6 antibody, NEK5 antibody, nek6.S antibody
    Background

    Synonyms: Highly similar to cell cycle protein kinase CDC5/MSD2, NEK6, NEK6_HUMAN, Never in mitosis A-related kinase 6, NIMA (Never In Mitosis Gene A) Related Kinase 6, NimA related protein kinase 6, NimA-related protein kinase 6, Protein kinase SID6 1512, Protein kinase SID6-1512, Putative serine threonine protein kinase, Serine/threonine protein kinase Nek6, Serine/threonine-protein kinase Nek6, SID61512.

    Background: Protein kinase which plays an important role in mitotic cell cycle progression. Required for chromosome segregation at metaphase-anaphase transition, robust mitotic spindle formation and cytokinesis. Phosphorylates ATF4, CIR1, PTN, RAD26L, RBBP6, RPS7, RPS6KB1, TRIP4, STAT3 and histones H1 and H3. Phosphorylates KIF11 to promote mitotic spindle formation. Involved in G2/M phase cell cycle arrest induced by DNA damage. Inhibition of activity results in apoptosis. May contribute to tumorigenesis by suppressing p53/TP53-induced cancer cell senescence.

    Gene ID
    10783
    UniProt
    Q9HC98
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