HSPBP1 antibody (AA 51-150)

Catalog No. ABIN6989222

Product Details anti-HSPBP1 Antibody

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Binding Specificity: AA 51-150

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSPBP1 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HspBP1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HSPBP1

Target: HSPBP1 (HSPA Binding Protein, Cytoplasmic Cochaperone 1 (HSPBP1))

Alternative Name: HspBP1 (HSPBP1 Products)

Synonyms: FES1 antibody, 1500019G21Rik antibody, HSPA (Hsp70) binding protein 1 antibody, HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 antibody, HSPBP1 antibody, Hspbp1 antibody

Background:

Synonyms: 1500019G21Rik, FES1, Heat shock protein 70 binding protein, Heat shock protein 70 interacting protein, Heat shock protein binding protein 1, Heat shock protein-binding protein 1, Heat-shock 70-KD protein-binding protein 1, HPBP1_HUMAN, Hsp 70 binding protein, Hsp 70 interacting protein, Hsp70 binding protein 1, Hsp70 binding protein 2, Hsp70 interacting protein 1, Hsp70 interacting protein 2, Hsp70-binding protein 1, Hsp70-binding protein 2, Hsp70-interacting protein 1, Hsp70-interacting protein 2, HSPA (heat shock 70 kDa) binding protein, cytoplasmic cochaperone 1, HSPA-binding protein 1, HSPBP, HspBP1, HspBP2, PP1845.

Background: Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.

Gene ID: 23640

UniProt: Q9NZL4