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TOP2B antibody (AA 1-100)

TOP2B Reactivity: Human, Rat ELISA, IHC (p), IF (p), IF (cc), ICC, IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6989203
  • Target See all TOP2B Antibodies
    TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
    Binding Specificity
    • 14
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 47
    • 18
    • 18
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Human, Rat
    Host
    • 46
    • 2
    Rabbit
    Clonality
    • 46
    • 1
    Polyclonal
    Conjugate
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TOP2B antibody is un-conjugated
    Application
    • 20
    • 15
    • 13
    • 12
    • 12
    • 8
    • 7
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Chimpanzee
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Topoisomerase II beta
    Isotype
    IgG
    Top Product
    Discover our top product TOP2B Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
    Alternative Name
    Topoisomerase II beta (TOP2B Products)
    Synonyms
    TOP2B antibody, D230016L12Rik antibody, Top-2 antibody, TOPIIB antibody, top2beta antibody, DNA topoisomerase II beta antibody, topoisomerase (DNA) II beta antibody, microRNA 4442 antibody, TOP2B antibody, Top2b antibody, MIR4442 antibody
    Background

    Synonyms: Antigen MLAA 44, beta isozyme, DNA topoisomerase 2 beta, DNA topoisomerase 2-beta, DNA topoisomerase II 180 kD, DNA topoisomerase II, DNA topoisomerase II beta, DNA topoisomerase II beta isozyme, Top 2, TOP 2B, TOP IIB, Top2 beta, TOP2B, TOP2B_HUMAN, Top2beta, TOPIIB, Topo II beta, Topoisomerase (DNA) II beta 180 kDa, Topoisomerase (DNA) II beta, Topoisomerase IIb, U937 associated antigen.

    Background: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

    Gene ID
    7155
    UniProt
    Q02880
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