FKBP1B antibody (AA 21-100)

Catalog No. ABIN6989185

Product Details anti-FKBP1B Antibody

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Binding Specificity: AA 21-100

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FKBP1B antibody is un-conjugated

Application: ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FKBP1B

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FKBP1B

Target: FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))

Alternative Name: FKBP1B (FKBP1B Products)

Synonyms: FKBP12.6 antibody, MGC68829 antibody, FKBP1B antibody, DKFZp459K1429 antibody, 12.6kDa antibody, AW494148 antibody, calstabin2 antibody, FKBP1L antibody, OTK4 antibody, PKBP1L antibody, PPIase antibody, FK506 binding protein 1B antibody, FK506 binding protein 1B L homeolog antibody, FK506 binding protein 1b antibody, FKBP1B antibody, fkbp1b.L antibody, fkbp1b antibody, Fkbp1b antibody

Background:

Synonyms: 12.6 kDa FK506-binding protein, 12.6 kDa FKBP, Calstabin 2, FK506 binding protein 1 like, FK506 binding protein 12.6, FK506 binding protein 1B 12.6 kDa, FK506 binding protein 1B, FK506-binding protein 1B, FKB1B_HUMAN, FKBP 12.6, FKBP 1B, FKBP 1L, FKBP 9, FKBP-12.6, FKBP-1B, FKBP12.6, Fkbp1b, FKBP1L, FKBP9, h FKBP 12, h-FKBP-12, Immunophilin FKBP12.6, OTK 4, OTK4, Peptidyl prolyl cis trans isomerase 1B, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP1B, PKBP 1L, PKBP1L, PPIase 1B, PPIase, PPIase FKBP1B, Rotamase 1B, Rotamase

Background: Associates with the ryanodine receptor (RYR-2) in cardiac muscle sarcoplasmic reticulum and may play a unique physiological role in excitation-contraction coupling in cardiac muscle. There are four molecules of FKBP12.6 per heart muscle RYR. Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Gene ID: 2281

UniProt: P68106

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity