CR1L antibody (AA 51-150) (FITC)
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- Target See all CR1L Antibodies
- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
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Binding Specificity
- AA 51-150
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CR1L antibody is conjugated to FITC
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Crry
- Isotype
- IgG
- Top Product
- Discover our top product CR1L Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CR1L (Complement Component (3b/4b) Receptor 1-Like (CR1L))
- Alternative Name
- Crry (CR1L Products)
- Synonyms
- CREG antibody, Cr1 antibody, Crry antibody, Mcp antibody, mCRY antibody, complement C3b/C4b receptor 1 like antibody, complement component (3b/4b) receptor 1-like antibody, CR1L antibody, Cr1l antibody
- Background
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Synonyms: Mcp, Crry, mCRY, Complement component receptor 1-like protein, Complement regulatory protein Crry, Protein p65, Cr1l, Cry
Background: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. Also acts as a decay-accelerating factor, preventing the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade. Plays a crucial role in early embryonic development by maintaining fetomaternal tolerance. Also acts as a costimulatory factor for T-cells which favors IL-4 secretion.
- Gene ID
- 12946
- UniProt
- Q64735
- Pathways
- Complement System
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