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YWHAB/YWHAZ antibody (pSer184, pSer186) (Cy7)

YWHAB/YWHAZ Reactivity: Human, Mouse, Rat WB, FACS, IF (cc), IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN6985867
  • Target See all YWHAB/YWHAZ products
    YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))
    Binding Specificity
    • 18
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    pSer184, pSer186
    Reactivity
    Human, Mouse, Rat
    Host
    • 20
    Rabbit
    Clonality
    • 20
    Polyclonal
    Conjugate
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This YWHAB/YWHAZ antibody is conjugated to Cy7
    Application
    • 20
    • 13
    • 12
    • 12
    • 8
    • 3
    • 3
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Predicted Reactivity
    Dog,Cow,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthesised phosphopeptide derived from human 14-3-3 beta + zeta around the phosphorylation site of Ser186 / Ser184
    Isotype
    IgG
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    YWHAB/YWHAZ (14-3-3 beta/zeta (YWHAB/YWHAZ))
    Alternative Name
    14-3-3 beta + zeta (YWHAB/YWHAZ Products)
    Synonyms
    14-3-3z antibody, 14-3-3zeta antibody, kcip-1 antibody, ywhaq antibody, Ywhaz antibody, ACYPI003154 antibody, 1433z antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta antibody, 14-3-3 protein zeta antibody, ywhaz antibody, 14-3-3zeta antibody, YWHAZ antibody, 1433z antibody
    Background

    Synonyms: 14-3-3 beta + zeta (phospho S184 + S186), 14-3-3 beta + zeta (phospho S186), 14-3-3 beta + zeta (phospho Ser186), p-14-3-3 beta + zeta (Ser186) 14 3 3 protein beta, 14 3 3 protein beta/alpha, 14 3 3 protein zeta/delta, 14 3 3 zeta, HS1, KCIP1, YWHAB, YWHAZ.

    Background: Members of the 14-3-3 family of proteins are highly conserved proteins, localized in neurons, and are axonally transported to the nerve terminals. They are also present, at lower levels, in various other eukaryotic tissues. 14-3-3 proteins appear to play important roles in a variety of signal transduction pathways, including those involved in cell cycle regulation and cell survival. Because 14-3-3 proteins bind to specific phosphoserine-containing sequences they are likely to have an important role in signaling pathways mediated by serine/threonine protein kinases. Evidence indicates 14-3-3 is required for Raf 1 kinase activity and phosphorylation amoung many other functions.

    Gene ID
    7529
    UniProt
    P31946
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