LPAR1 antibody (AA 1-50) (Biotin)

Catalog No. ABIN6982846

Product Details anti-LPAR1 Antibody (Biotin)

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Binding Specificity: AA 1-50

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LPAR1 antibody is conjugated to Biotin

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPA1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for LPAR1

Target: LPAR1 (Lysophosphatidic Acid Receptor 1 (LPAR1))

Alternative Name: LPA1 (LPAR1 Products)

Background:

Synonyms: EDG 2, Endothelial Cell Differentiation Gene-2, Endothelial differentiation gene 2, Endothelial Differentiation Lysophosphatidic Acid G Protein Coupled Receptor 2, G10 protein homolog, GPCR 26, GPCR26, Gpcr91, Kdt2, LPA 1, LPA receptor 1, LPA receptor EDG2, LPA1, LPAR1, Lysophosphatidic acid receptor 1, Lysophosphatidic acid receptor EDG2, MGC105279, MGC29102, LPAR1_HUMAN.

Background: Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Stimulates phospholipase C (PLC) activity in a manner that is dependent on RALA activation.

Gene ID: 1902

UniProt: Q92633

Pathways: Myometrial Relaxation and Contraction, Smooth Muscle Cell Migration