PURA antibody (AA 131-230) (Biotin)

Catalog No. ABIN6982721

Product Details anti-PURA Antibody (Biotin)

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Binding Specificity: AA 131-230

Reactivity: Mouse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PURA antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse, Zebrafish (Danio rerio)

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Cat,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PURA

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for PURA

Target: PURA (Purine-Rich Element Binding Protein A (PURA))

Alternative Name: PURA (PURA Products)

Synonyms: CAGER-1 antibody, Pur-alpha antibody, ssCRE-BP antibody, PUR-ALPHA antibody, PUR1 antibody, PURALPHA antibody, zgc:103411 antibody, pur-alpha antibody, pur1 antibody, puralpha antibody, purine-rich element binding protein A antibody, purine rich element binding protein A antibody, purine-rich element binding protein Aa antibody, purine-rich element binding protein A L homeolog antibody, pura antibody, Pura antibody, PURA antibody, puraa antibody, pura.L antibody

Background:

Synonyms: PUR ALPHA, PUR1, purA, PURA_HUMAN, PURALPHA, Purine rich element binding protein A, Purine rich single stranded DNA binding protein alpha, Purine-rich single-stranded DNA-binding protein alpha, Transcriptional activator protein PUR alpha, Transcriptional activator protein Pur-alpha.

Background: This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]

Gene ID: 5813

UniProt: Q00577