HSD17B11 antibody (AA 201-300) (Biotin)

Catalog No. ABIN6982651

Product Details anti-HSD17B11 Antibody (Biotin)

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Binding Specificity: AA 201-300

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSD17B11 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Hsd17b11

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSD17B11

Target: HSD17B11 (Hydroxysteroid (17-Beta) Dehydrogenase 11 (HSD17B11))

Alternative Name: HSD17B11 (HSD17B11 Products)

Background:

Synonyms: 17 beta HSD 11, 17 beta HSD XI, 17 BETA HSD11, 17 BETA HSDXI, 17 beta hydroxysteroid dehydrogenase 11, 17 beta hydroxysteroid dehydrogenase type XI, 17 beta hydroxysteroid dehydrogenase XI, 17-beta-HSD 11, 17-beta-HSD XI, 17-beta-hydroxysteroid dehydrogenase 11, 17-beta-hydroxysteroid dehydrogenase XI, 17betaHSD11, 17betaHSDXI, 17bHSD11, CTCL associated antigen HD CL 03, CTCL tumor antigen HD CL 03, CTCL-associated antigen HD-CL-03, Cutaneous T cell lymphoma associated antigen HD CL 03, Cutaneous T-cell lymphoma-associated antigen HD-CL-03, Dehydrogenase/reductase SDR family member 8, DHB11_HUMAN, DHRS8, Estradiol 17 beta dehydrogenase 11, Estradiol 17-beta-dehydrogenase 11, Hsd17b11, Hydroxysteroid (17 beta) dehydrogenase 11, PAN1B, Retinal short chain dehydrogenase/reductase 2, Retinal short-chain dehydrogenase/reductase 2, RETSDR2, SDR16C2, SDR2, Short chain dehydrogenase/reductase family 16C member 2, T cell lymphoma associated antigen HD CL 03, 17_-HSD11.

Background: Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Gene ID: 51170

UniProt: Q8NBQ5