HS2ST1 antibody (AA 221-320) (Biotin)

Catalog No. ABIN6982650

Product Details anti-HS2ST1 Antibody (Biotin)

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Binding Specificity: AA 221-320

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HS2ST1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HS2ST1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HS2ST1

Target: HS2ST1 (Heparan Sulfate 2-O-Sulfotransferase 1 (HS2ST1))

Alternative Name: HS2ST1 (HS2ST1 Products)

Synonyms: HS2ST1 antibody, hs2st antibody, dJ604K5.2 antibody, AW214369 antibody, Hs2st antibody, mKIAA0448 antibody, CHS2ST antibody, HS2ST antibody, 2-OST antibody, 2OST antibody, HS2st antibody, hs2st1 antibody, im:7147474 antibody, zgc:158230 antibody, heparan sulfate 2-O-sulfotransferase 1 antibody, Heparan sulfate 2-O-sulfotransferase 1 antibody, heparan sulfate 2-O-sulfotransferase 1 L homeolog antibody, heparan sulfate 2-O-sulfotransferase 1a antibody, HS2ST1 antibody, Tsp_05909 antibody, hs2st1 antibody, hs2st antibody, Hs2st1 antibody, hs2st1.L antibody, hs2st1a antibody

Background:

Synonyms: 2-O-sulfotransferase, 2OST, dJ604K5.2, FLJ11317, heparan sulfate 2 O sulfotransferase 1, Heparan sulfate 2-O-sulfotransferase 1, HS2ST_HUMAN, hs2st1, KIAA0448, MGC131986.

Background: Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate biosynthetic enzymes. HS2ST1 is a 356 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the sulfotransferase 3 family. Expressed as multiple alternatively spliced isoforms, HS2ST1 functions to catalyze the transfer of sulfate groups to hexuronic acid residues within maturing heparan sulfate (HS), an event which is crucial for proper HS-related ligand binding and signaling processes. HS2ST1 is subject to post-translational N-glycosylation and, in addition to its role in HS function, may be involved in proper kidney formation.

Gene ID: 9653

UniProt: Q7LGA3

Pathways: Glycosaminoglycan Metabolic Process, Tube Formation, SARS-CoV-2 Protein Interactome