HnRNP M1-M4 (AA 641-730) antibody (Biotin)

Catalog No. ABIN6982646

Product Details

Target: HnRNP M1-M4

Binding Specificity: AA 641-730

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human hnRNP M1-M4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details

Target: HnRNP M1-M4

Background:

Synonyms: CEA receptor, CEAR, DKFZp547H118, Heterogeneous nuclear ribonucleoprotein M, Heterogeneous nuclear ribonucleoprotein M4, Heterogenous nuclear ribonucleoprotein M4, hnRNA binding protein M4, hnRNP M, Hnrnpm, HNRNPM4, HNRPM, HNRPM_HUMAN, HNRPM4, HTGR1, N acetylglucosamine receptor 1, NAGR1.

Background: Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines.

Gene ID: 4670

UniProt: P52272