HIV-1 p17/p24/p55 (AA 231-330) antibody (AbBy Fluor® 680)

Catalog No. ABIN6981457

Product Details

Target: HIV-1 p17/p24/p55

Binding Specificity: AA 231-330

Reactivity: Human Immunodeficiency Virus (HIV), Virus

Host: Rabbit

Clonality: Polyclonal

Conjugate: AbBy Fluor® 680

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Virus

Cross-Reactivity (Details): HIV1

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from HIV1 Pr55Gag

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: HIV-1 p17/p24/p55

Alternative Name: HIV1 p55+p24+p17

Target Type: Viral Protein

Background:

Synonyms: HIV p55+Capsid protein p24, HIV1 p55 + p24 + p17, CA antibody Capsid protein p24, Gag, Gag polyprotein, HIV1 matrix protein p17, HIV1 Pr55Gag, Human immunodeficiency virus 1 p17, Human immunodeficiency virus 1 p55, Human immunodeficiency virus type 1 p24, MA antibody Matrix protein, Matrix protein p17, Pr55, Pr55Gag, POL_HV1H2.

Background: HIV1 performs highly complex orchestrated tasks during the assembly, budding, maturation and infection stages of the viral replication cycle. During viral assembly, the proteins form membrane associations and self-associations that ultimately result in budding of an immature virion from the infected cell. Gag precursors also function during viral assembly to selectively bind and package two plus strands of genomic RNA. p55 is digested by HIV1 protease into intermediate products p41 and p15. p41 is further digested into matrix protein p17 and capsid protein p24. Likewise, p15 is further digested into nucleocapsid protein p7 and to p6 and p1.