Melatonin Receptor 1A antibody (AA 181-280) (AbBy Fluor® 680)

Catalog No. ABIN6981313

Product Details anti-Melatonin Receptor 1A Antibody (AbBy Fluor® 680)

Target: Melatonin Receptor 1A (MTNR1A)

Binding Specificity: AA 181-280

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Melatonin Receptor 1A

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: Melatonin Receptor 1A (MTNR1A Products)

Background:

Synonyms: Mel 1A R, Mel1a melatonin receptor, Mel1a receptor, MEL-1A-R, Melatonin receptor type 1A, MelR, MR, MT 1, MT1, MTNR 1A, MTNR1A, Melatonin receptor 1A, MTR1A_HUMAN, MTR-1A.

Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

Gene ID: 4543

UniProt: P48039