PTPN21 antibody (AA 171-270) (AbBy Fluor® 680)
-
- Target See all PTPN21 Antibodies
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
-
Binding Specificity
- AA 171-270
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This PTPN21 antibody is conjugated to AbBy Fluor® 680
-
Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PTPD1
- Isotype
- IgG
- Top Product
- Discover our top product PTPN21 Primary Antibody
-
-
- Application Notes
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
-
- Target
- PTPN21 (Protein tyrosine Phosphatase, Non-Receptor Type 21 (PTPN21))
- Alternative Name
- PTPD1 (PTPN21 Products)
- Synonyms
- PTPD1 antibody, PTPRL10 antibody, Ptp2E antibody, protein tyrosine phosphatase, non-receptor type 21 antibody, PTPN21 antibody, Ptpn21 antibody
- Background
-
Synonyms: Protein tyrosine phosphatase D1, Protein tyrosine phosphatase non receptor type 21, PTPN 21, PTPN21, PTN21_HUMAN, PTPNL, PTPRL10, Tyrosine protein phosphatase non receptor type 21.
Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis. [provided by RefSeq, Jul 2008]
- Gene ID
- 11099
- UniProt
- Q16825
-