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ERO1LB antibody (AA 1-100) (AbBy Fluor® 680)

ERO1LB Reactivity: Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 680
Catalog No. ABIN6980837
  • Target See all ERO1LB Antibodies
    ERO1LB (ERO1-Like beta (ERO1LB))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 1
    • 1
    AA 1-100
    Reactivity
    • 25
    • 23
    • 16
    Mouse, Rat
    Host
    • 37
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERO1LB antibody is conjugated to AbBy Fluor® 680
    Application
    • 33
    • 20
    • 17
    • 13
    • 12
    • 12
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Pig,Rabbit,Guinea Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ERO1LB
    Isotype
    IgG
    Top Product
    Discover our top product ERO1LB Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ERO1LB (ERO1-Like beta (ERO1LB))
    Alternative Name
    ERO1LB (ERO1LB Products)
    Synonyms
    RGD1563548 antibody, 1300013B24Rik antibody, 1700065B09Rik antibody, AI447560 antibody, ero1-beta antibody, endoplasmic reticulum oxidoreductase 1 beta antibody, ERO1-like beta (S. cerevisiae) antibody, Ero1b antibody, ERO1B antibody, Ero1lb antibody
    Background

    Synonyms: Endoplasmic oxidoreductin-1-like protein B, ERO1-L-beta, ERO1B, ERO1-like protein beta, Oxidoreductin-1-L-beta

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Other protein disulfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50 % of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10 %). Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsulin folding in pancreatic cells, hence may play a role in glucose homeostasis.

    Gene ID
    56605
    UniProt
    Q86YB8
    Pathways
    SARS-CoV-2 Protein Interactome
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