MREG antibody (AA 101-200) (AbBy Fluor® 680)

Catalog No. ABIN6980816

Product Details anti-MREG Antibody (AbBy Fluor® 680)

Target: MREG (Melanoregulin (MREG))

Binding Specificity: AA 101-200

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MREG antibody is conjugated to AbBy Fluor® 680

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DSU

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MREG

Target: MREG (Melanoregulin (MREG))

Alternative Name: DSU (MREG Products)

Synonyms: MGC115366 antibody, DSU antibody, WDT2 antibody, Gm974 antibody, Wdt2 antibody, dsu antibody, RGD1562333 antibody, mreg antibody, wu:fk68c04 antibody, melanoregulin antibody, melanoregulin L homeolog antibody, zgc:91968 antibody, MREG antibody, mreg antibody, mreg.L antibody, Mreg antibody, zgc:91968 antibody

Background:

Synonyms: Dilute suppressor, Dilute suppressor protein homolog, DSU, FLJ10116, MREG_HUMAN, Melanoregulin, MGC90296, MREG, OTTHUMP00000206794, OTTHUMP00000206795, OTTHUMP00000206796, WDT 2, WDT2, Whn dependent transcript 2.

Background: The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG (melanoregulin), also known as DSU (dilute suppressor protein homolog) or WDT2, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

Gene ID: 55686

UniProt: Q8N565