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MREG antibody (AA 101-200) (AbBy Fluor® 647)

MREG Reactivity: Mouse, Rat WB, IF (p), IF (cc) Host: Rabbit Polyclonal AbBy Fluor® 647
Catalog No. ABIN6979919
  • Target See all MREG Antibodies
    MREG (Melanoregulin (MREG))
    Binding Specificity
    • 18
    • 15
    • 14
    • 1
    • 1
    • 1
    AA 101-200
    Reactivity
    • 36
    • 32
    • 30
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Mouse, Rat
    Host
    • 45
    • 5
    Rabbit
    Clonality
    • 47
    • 3
    Polyclonal
    Conjugate
    • 14
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This MREG antibody is conjugated to AbBy Fluor® 647
    Application
    • 40
    • 25
    • 12
    • 11
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human DSU
    Isotype
    IgG
    Top Product
    Discover our top product MREG Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MREG (Melanoregulin (MREG))
    Alternative Name
    DSU (MREG Products)
    Synonyms
    MGC115366 antibody, DSU antibody, WDT2 antibody, Gm974 antibody, Wdt2 antibody, dsu antibody, RGD1562333 antibody, mreg antibody, wu:fk68c04 antibody, melanoregulin antibody, melanoregulin L homeolog antibody, zgc:91968 antibody, MREG antibody, mreg antibody, mreg.L antibody, Mreg antibody, zgc:91968 antibody
    Background

    Synonyms: Dilute suppressor, Dilute suppressor protein homolog, DSU, FLJ10116, MREG_HUMAN, Melanoregulin, MGC90296, MREG, OTTHUMP00000206794, OTTHUMP00000206795, OTTHUMP00000206796, WDT 2, WDT2, Whn dependent transcript 2.

    Background: The photoreceptor rod cell that is responsible for vision under conditions of low light consists of stacked arrays of disk membranes that make up its outer segment portion. Regulated by complex biochemical mechanisms, the rod outer segment is under constant renewal as new disks form at the base. MREG (melanoregulin), also known as DSU (dilute suppressor protein homolog) or WDT2, is thought to play a role in membrane fusion and in regulating the biogenesis of disk membranes of photoreceptor rods. MREG interacts with RDS (also known as Peripherin-2), a photoreceptor specific tetraspanin protein that is required to maintain normal cell structure during the renewal process of membrane fusion. MREG is 214 amino acids in length, is expressed in photoreceptor cells and and is expressed as two isoforms due to alternative splicing.

    Gene ID
    55686
    UniProt
    Q8N565
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