TNP1 antibody (AA 201-300) (AbBy Fluor® 555)
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- Target See all TNP1 Antibodies
- TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))
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Binding Specificity
- AA 201-300
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TNP1 antibody is conjugated to AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from mouse Transition Protein 1
- Isotype
- IgG
- Top Product
- Discover our top product TNP1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))
- Alternative Name
- Transition Protein 1 (TNP1 Products)
- Synonyms
- TNP1 antibody, TP1 antibody, Stp-1 antibody, Tp-1 antibody, STP-1 antibody, TP-1 antibody, transition protein 1 antibody, TNP1 antibody, Tnp1 antibody
- Background
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Synonyms: 551G9.2, Anti Eukaryotic Release Factor 3a, Anti G1 to S phase transition 1, Anti GST1, homolog of yeast, eRF 3a, eRF3a, G1 to S phase transition 1, G1 to S phase transition protein 1 homolog, G1 to S phase transition protein, GSPT 1, GSPT1, GST 1, GST1, GTP binding protein GST1 HS, Transition protein 1, ERF3A_MOUSE.
Background: eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
- Gene ID
- 14852
- UniProt
- P15170
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