NUDCD1 antibody (AA 431-530) (AbBy Fluor® 555)
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- Target See all NUDCD1 products
- NUDCD1 (NudC Domain Containing 1 (NUDCD1))
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Binding Specificity
- AA 431-530
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NUDCD1 antibody is conjugated to AbBy Fluor® 555
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat,Dog,Cow,Sheep,Horse,Rabbit,Zebrafish
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human NUDCD1
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- NUDCD1 (NudC Domain Containing 1 (NUDCD1))
- Alternative Name
- NUDCD1 (NUDCD1 Products)
- Synonyms
- Cml66 antibody, NUDCD1 antibody, CML66 antibody, OVA66 antibody, 4921532K09Rik antibody, AA407246 antibody, AW260430 antibody, AW556235 antibody, CML66-L antibody, RGD1310624 antibody, im:6901299 antibody, im:6912119 antibody, wu:fc11c02 antibody, zgc:110705 antibody, cml66 antibody, NudC domain containing 1 antibody, NudC domain-containing protein 1 antibody, NudC domain containing 1 S homeolog antibody, NUDCD1 antibody, nudcd1 antibody, CpipJ_CPIJ019282 antibody, nudc1 antibody, LOC777229 antibody, Nudcd1 antibody, nudcd1.S antibody
- Background
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Synonyms: 4921532K09Rik, AA407246, AW260430, AW556235, Chronic myelogenous leukemia tumor antigen 66, CML66, CML66 L, FLJ14991, NudC domain containing 1, NudC domain-containing protein 1, NUDC1_HUMAN, nudcd1, OVA66, RGD1310624, Tumor antigen CML66.
Background: The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38 % of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.
- Gene ID
- 84955
- UniProt
- Q96RS6
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