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NUDCD1 antibody (AA 431-530) (AbBy Fluor® 555)

NUDCD1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 555
Catalog No. ABIN6978553
  • Target See all NUDCD1 products
    NUDCD1 (NudC Domain Containing 1 (NUDCD1))
    Binding Specificity
    • 14
    • 7
    • 7
    • 6
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 431-530
    Reactivity
    • 22
    • 20
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Mouse
    Host
    • 36
    Rabbit
    Clonality
    • 36
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NUDCD1 antibody is conjugated to AbBy Fluor® 555
    Application
    • 36
    • 16
    • 12
    • 12
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Horse,Rabbit,Zebrafish
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human NUDCD1
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    NUDCD1 (NudC Domain Containing 1 (NUDCD1))
    Alternative Name
    NUDCD1 (NUDCD1 Products)
    Synonyms
    Cml66 antibody, NUDCD1 antibody, CML66 antibody, OVA66 antibody, 4921532K09Rik antibody, AA407246 antibody, AW260430 antibody, AW556235 antibody, CML66-L antibody, RGD1310624 antibody, im:6901299 antibody, im:6912119 antibody, wu:fc11c02 antibody, zgc:110705 antibody, cml66 antibody, NudC domain containing 1 antibody, NudC domain-containing protein 1 antibody, NudC domain containing 1 S homeolog antibody, NUDCD1 antibody, nudcd1 antibody, CpipJ_CPIJ019282 antibody, nudc1 antibody, LOC777229 antibody, Nudcd1 antibody, nudcd1.S antibody
    Background

    Synonyms: 4921532K09Rik, AA407246, AW260430, AW556235, Chronic myelogenous leukemia tumor antigen 66, CML66, CML66 L, FLJ14991, NudC domain containing 1, NudC domain-containing protein 1, NUDC1_HUMAN, nudcd1, OVA66, RGD1310624, Tumor antigen CML66.

    Background: The NUDCD1 gene encodes the 583 amino acid CML66 protein which demonstrates expression in a variety of solid tumor cell lines and leukemias. Expression of CML66 in normal tissues is restricted to testis and heart. The CML66 antibody is found in sera of 18-38 % of patients with lung cancer, melanoma or prostate cancer. These findings indicate that CML66 may be immunogenic in a wide variety of malignancies and may be a target for antigen-specific immunotherapy. A short isoform of CML66, designated CML66-S, is a product of alternative splicing. CML66-S has the same C-terminus as full-lenghth CML66 (also designated CML66-L), but has a unique N-terminus. CML66-S shows predominant expression in testis, and is also expressed in very low levels in tumor cells, while CML66 is expressed in tumor cells and testis.

    Gene ID
    84955
    UniProt
    Q96RS6
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