SNF8 antibody (AA 31-130) (AbBy Fluor® 555)
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- Target See all SNF8 Antibodies
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
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Binding Specificity
- AA 31-130
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SNF8 antibody is conjugated to AbBy Fluor® 555
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EAP30
- Isotype
- IgG
- Top Product
- Discover our top product SNF8 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))
- Alternative Name
- EAP30 (SNF8 Products)
- Synonyms
- d11moh34 antibody, vps22 antibody, Dot3 antibody, EAP30 antibody, VPS22 antibody, D11moh34 antibody, RGD1310144 antibody, D11Moh34 antibody, D11MOH34 antibody, zgc:101578 antibody, SNF8, ESCRT-II complex subunit antibody, eap30 subunit of ell complex, putative antibody, EAP30 subunit of ELL complex antibody, SNF8, ESCRT-II complex subunit S homeolog antibody, SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) antibody, snf8 antibody, TA17290 antibody, TVAG_107410 antibody, Bm1_05145 antibody, SNF8 antibody, Snf8 antibody, snf8.S antibody
- Background
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Synonyms: Dot3, ELL associated protein of 30 kDa, ELL-associated protein of 30 kDa, ESCRT-II complex subunit VPS22, hVps22, snf8, SNF8 ESCRTII complex subunit homolog (S cerevisiae), SNF8_HUMAN, Vacuolar sorting protein SNF8, Vacuolar-sorting protein SNF8, VPS22.
Background: Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex is probably involved in the recruitment of the ESCRT-III complex. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Required for degradation of both endocytosed EGF and EGFR, but not for the EGFR ligand-mediated internalization. It is also required for the degradation of CXCR4.
- Gene ID
- 11267
- UniProt
- Q96H20
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