MOXD1 antibody (AA 501-600) (AbBy Fluor® 488)

Catalog No. ABIN6977568

Product Details anti-MOXD1 Antibody (AbBy Fluor® 488)

Target: MOXD1 (Monooxygenase, DBH-Like 1 (MOXD1))

Binding Specificity: AA 501-600

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MOXD1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MOXD1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MOXD1

Target: MOXD1 (Monooxygenase, DBH-Like 1 (MOXD1))

Alternative Name: MOXD1 (MOXD1 Products)

Synonyms: MOX antibody, PRO5780 antibody, dJ248E1.1 antibody, 3230402N08Rik antibody, MNCb-5203 antibody, DBHR antibody, monooxygenase, DBH-like 1 antibody, monooxygenase DBH like 1 antibody, Moxd1 antibody, MOXD1 antibody

Background:

Synonyms: DBH like monooxygenase protein 1, DBH-like monooxygenase protein 1, dJ248E1.1, DKFZp564G202, Monooxygenase X, monooxygenase, DBH like 1, MOX, Moxd1, MOXD1_HUMAN, PRO5780.

Background: MOXD1 is a 613 amino acid single-pass type I membrane protein of the Endoplasmic reticulum that belongs to the copper type II ascorbate-dependent monooxygenase family. Existing as two alternatively spliced isoforms, MOXD1 is expressed in adult spinal cord, adrenal gland, brain, testis, uterus, lung and kidney, as well as fetal liver and brain. MOXD1 is upregulated during replicative senescence in primary fibroblast and umbilical vein endothelial cell cultures, and uses two copper ions per subunit as a cofactor. MOXD1 contains one DOMON domain, undergoes post-translational N-glycosylation and is encoded by a gene that maps to human chromosome 6. Chromosome 6 contains 170 million base pairs, comprises nearly 6 % of the human genome and is associated with early onset intestinal cancer, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome.

Gene ID: 26002

UniProt: Q6UVY6