SBNO1 antibody (AA 331-430) (AbBy Fluor® 488)

Catalog No. ABIN6977519

Product Details anti-SBNO1 Antibody (AbBy Fluor® 488)

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Binding Specificity: AA 331-430

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SBNO1 antibody is conjugated to AbBy Fluor® 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SBNO1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SBNO1

Target: SBNO1 (Strawberry Notch Homolog 1 (SBNO1))

Alternative Name: SBNO1 (SBNO1 Products)

Synonyms: 9330180L10Rik antibody, AI849128 antibody, AW557836 antibody, BC021875 antibody, Sbno antibody, mSno1 antibody, sno antibody, MOP3 antibody, Sno antibody, strawberry notch homolog 1 (Drosophila) antibody, strawberry notch homolog 1 antibody, microRNA 8072 antibody, Sbno1 antibody, SBNO1 antibody, MIR8072 antibody

Background:

Synonyms: FLJ10701, FLJ10833, FLJ16176, Monocyte protein 3, MOP 3, MOP-3, MOP3, Protein strawberry notch homolog 1, SBNO 1, Sbno1, SBNO1_HUMAN, Sno, Sno strawberry notch homolog 1, Strawberry notch homolog 1.

Background: SBNO1 is a 1,392 amino acid protein encoded by the human gene of the same name located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster, which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster, encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms which vary in severity depending on the extent of mosaicism. It is most severe in cases of complete trisomy.

Gene ID: 55206

UniProt: A3KN83

Pathways: SARS-CoV-2 Protein Interactome