CYP8B1 antibody (AA 151-250) (AbBy Fluor® 488)
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- Target See all CYP8B1 Antibodies
- CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))
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Binding Specificity
- AA 151-250
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CYP8B1 antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Cow,Sheep,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human CYP8B1
- Isotype
- IgG
- Top Product
- Discover our top product CYP8B1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- CYP8B1 (Cytochrome P450, Family 8, Subfamily B, Polypeptide 1 (CYP8B1))
- Alternative Name
- CYP8B1 (CYP8B1 Products)
- Synonyms
- MGC64456 antibody, CYP8B antibody, CP8B antibody, CYP12 antibody, cytochrome P450 family 8 subfamily B member 1 antibody, cytochrome P450 family 8 subfamily B member 1 S homeolog antibody, cytochrome P450, family 8, subfamily B, polypeptide 1 antibody, cytochrome P450, family 8, subfamily b, polypeptide 1 antibody, Cyp8b1 antibody, cyp8b1.S antibody, CYP8B1 antibody
- Background
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Synonyms: 7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase, 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase, CP8B1_HUMAN, CYP12, CYP8B1, CYPVIIIB1, Cytochrome P450 8B1, Cytochrome P450, family 8, subfamily B, polypeptide 1, Sterol 12-alpha-hydroxylase.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
- Gene ID
- 1582
- UniProt
- Q9UNU6
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