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ERO1L antibody (AA 321-420) (AbBy Fluor® 488)

ERO1L Reactivity: Human WB, FACS Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN6977263
  • Target See all ERO1L Antibodies
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Binding Specificity
    • 15
    • 7
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-420
    Reactivity
    • 43
    • 4
    • 4
    Human
    Host
    • 37
    • 5
    • 1
    Rabbit
    Clonality
    • 40
    • 2
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ERO1L antibody is conjugated to AbBy Fluor® 488
    Application
    • 43
    • 22
    • 19
    • 15
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ERO1L
    Isotype
    IgG
    Top Product
    Discover our top product ERO1L Primary Antibody
  • Application Notes
    FCM 1:20-100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    ERO1L (ERO1-Like Protein alpha (ERO1L))
    Alternative Name
    ERO1L (ERO1L Products)
    Synonyms
    ERO1-L antibody, ero1-alpha antibody, ero1lb antibody, ERO1L antibody, ero1l antibody, ERO1-alpha antibody, ERO1A antibody, zgc:63959 antibody, endoplasmic reticulum oxidoreductase alpha L homeolog antibody, endoplasmic reticulum oxidoreductase 1 alpha antibody, endoplasmic reticulum oxidoreductase alpha antibody, ERO1-like (S. cerevisiae) antibody, ero1a.L antibody, ERO1A antibody, ero1a antibody, Ero1l antibody, Ero1a antibody
    Background

    Synonyms: ERO1-like protein alpha, ERO1A, ERO1-L, ERO1-L-alpha, Endoplasmic oxidoreductin-1-like protein, Endoplasmic reticulum oxidoreductase alpha, Oxidoreductin-1-L-alpha, ERO1L

    Background: Oxidoreductase involved in disulfide bond formation in the endoplasmic reticulum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disulfide formation, in order to allow P4HB to sustain additional rounds of disulfide formation. Following P4HB reoxidation, passes its electrons to molecular oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. Required for the proper folding of immunoglobulins. Involved in the release of the unfolded cholera toxin from reduced P4HB/PDI in case of infection by V.cholerae, thereby playing a role in retrotranslocation of the toxin. Plays an important role in ER stress-induced, CHOP-dependent apoptosis by activating the inositol 1,4,5-trisphosphate receptor IP3R1.

    Gene ID
    30001
    UniProt
    Q96HE7
    Pathways
    Peptide Hormone Metabolism, ER-Nucleus Signaling, Brown Fat Cell Differentiation
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