OPA3 antibody (AA 1-100) (AbBy Fluor® 350)

Catalog No. ABIN6976998

Product Details anti-OPA3 Antibody (AbBy Fluor® 350)

Target: OPA3 (Optic Atrophy 3 (Autosomal Recessive, with Chorea and Spastic Paraplegia) (OPA3))

Binding Specificity: AA 1-100

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OPA3 antibody is conjugated to AbBy Fluor® 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Dog,Cow,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human OPA3

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for OPA3

Target: OPA3 (Optic Atrophy 3 (Autosomal Recessive, with Chorea and Spastic Paraplegia) (OPA3))

Alternative Name: OPA3 (OPA3 Products)

Synonyms: D630048P19Rik antibody, Gm1425 antibody, Gm472 antibody, MGA3 antibody, optic atrophy 3 antibody, OPA3, outer mitochondrial membrane lipid metabolism regulator antibody, opa3 antibody, Opa3 antibody, OPA3 antibody

Background:

Synonyms: FLJ22187, FLJ25932, Iraqi Jewish optic atrophy plus (3 methylglutaconicaciduria type 3), MGA3, MGC75494, OPA 3, OPA3 protein, Optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia), Optic atrophy 3 (Iraqi Jewish 'optic atrophy plus'), Optic atrophy 3, Optic atrophy 3 protein.

Background: OPA3 may play some role in mitochondrial processes. Defects in OPA3 are the cause of 3-methylglutaconic aciduria type 3 (MGA3), also known as optic atrophy plus syndrome, and of optic atrophy type 3 (OPA3), also known as autosomal dominant optic atrophy and cataract (ADOAC).

Gene ID: 80207

UniProt: Q9H6K4