OMA1 antibody (AA 401-500) (AbBy Fluor® 350)
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- Target See all OMA1 Antibodies
- OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))
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Binding Specificity
- AA 401-500
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This OMA1 antibody is conjugated to AbBy Fluor® 350
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse, Rat
- Predicted Reactivity
- Cow,Pig,Horse,Chicken,Cat,Rabbit,Zebrafish
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human OMA1
- Isotype
- IgG
- Top Product
- Discover our top product OMA1 Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- OMA1 (OMA1 Zinc Metallopeptidase Homolog (OMA1))
- Alternative Name
- OMA1 (OMA1 Products)
- Synonyms
- 2010001O09Rik antibody, DAB1 antibody, MPRP-1 antibody, YKR087C antibody, ZMPOMA1 antibody, peptidase antibody, RGD1304821 antibody, oma1 antibody, OMA1 zinc metallopeptidase antibody, si:ch73-215a11.1 antibody, olfactory receptor 4K2 antibody, OMA1 antibody, Oma1 antibody, si:ch73-215a11.1 antibody, LOC531304 antibody
- Background
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Synonyms: Metalloendopeptidase OMA1, mitochondrial, OMA1, Metalloprotease-related protein 1, MPRP-1, Overlapping with the m-AAA protease 1 homolog, OMA1, MPRP1
Background: Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. May also cleave UQCC3 under these conditions. Its role in mitochondrial quality control is essential for regulating lipid metabolism as well as to maintain body temperature and energy expenditure under cold-stress conditions.
- Gene ID
- 115209
- UniProt
- Q96E52
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