TOP2B antibody (AA 1-100) (AbBy Fluor® 350)
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- Target See all TOP2B Antibodies
- TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
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Binding Specificity
- AA 1-100
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Reactivity
- Human, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TOP2B antibody is conjugated to AbBy Fluor® 350
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Application
- Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human, Rat
- Predicted Reactivity
- Mouse,Dog,Cow,Sheep,Pig,Horse,Rabbit,Chimpanzee
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Topoisomerase II beta
- Isotype
- IgG
- Top Product
- Discover our top product TOP2B Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- TOP2B (Topoisomerase (DNA) II beta 180kDa (TOP2B))
- Alternative Name
- Topoisomerase II beta (TOP2B Products)
- Synonyms
- TOP2B antibody, D230016L12Rik antibody, Top-2 antibody, TOPIIB antibody, top2beta antibody, DNA topoisomerase II beta antibody, topoisomerase (DNA) II beta antibody, microRNA 4442 antibody, TOP2B antibody, Top2b antibody, MIR4442 antibody
- Background
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Synonyms: Antigen MLAA 44, beta isozyme, DNA topoisomerase 2 beta, DNA topoisomerase 2-beta, DNA topoisomerase II 180 kD, DNA topoisomerase II, DNA topoisomerase II beta, DNA topoisomerase II beta isozyme, Top 2, TOP 2B, TOP IIB, Top2 beta, TOP2B, TOP2B_HUMAN, Top2beta, TOPIIB, Topo II beta, Topoisomerase (DNA) II beta 180 kDa, Topoisomerase (DNA) II beta, Topoisomerase IIb, U937 associated antigen.
Background: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly ivolved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
- Gene ID
- 7155
- UniProt
- Q02880
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