Sox11 (SRY-box containing protein 11) is a member of a family of transcription factors containing an HMG DNA-binding domain. Sox11 is important for the development of nervous system. Sox11 is upregulated in a variety of tumor types, including medulloblastomas, gliomas and epithelial ovarian tumors. In B cell lymphomas, information regarding the expression of Sox11 aids in diagnosis and prognosis. Sox11 also functions as a tumor suppressor in glioma-initiating cells. Sox11 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
Purification
Affinity Purified
Immunogen
This Sox11 antibody was raised against a peptide from the N-terminus of human Sox11.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Buffer
Purified rabbit IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
Target
SOX11
(SRY (Sex Determining Region Y)-Box 11 (SOX11))