JMJD6 antibody (N-Term)

Catalog No. ABIN6972238

Product Details anti-JMJD6 Antibody

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This JMJD6 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: JMJD6 (Jumonji Domain-Containing Protein 6) is a dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. JMJD6 acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. Required for differentiation of multiple organs during embryogenesis and acts as a key regulator of hematopoietic differentiation. May act as a RNA hydroxylase, as suggested by its ability to bind single strand RNA. JMJD6 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the N-terminal region of human JMJD6.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for JMJD6

Target: JMJD6 (Jumonji Domain Containing 6 (JMJD6))

Alternative Name: JMJD6 (JMJD6 Products)

Molecular Weight: 52 kDa

NCBI Accession: NP_001074930