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GLYR1 antibody (C-Term)

GLYR1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6971688
  • Target See all GLYR1 Antibodies
    GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
    Binding Specificity
    • 15
    • 2
    • 1
    • 1
    C-Term
    Reactivity
    • 29
    • 25
    • 10
    Human
    Host
    • 27
    • 2
    Rabbit
    Clonality
    • 29
    Polyclonal
    Conjugate
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GLYR1 antibody is un-conjugated
    Application
    • 21
    • 13
    • 13
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Characteristics
    GLYR1 / NDF (nucleosome-destabilizing factor) that is recruited to gene bodies during transcriptional activation and facilitates Pol II transcription through nucleosomes, where it is proposed to ""unzip"" chromatin during transcription, pushing the polymerase past pause points. It was discovered as a factor that allows p300 to acetylate Histone H3K56, which is normally an inaccessible residue for this modification. GLYR1 is shown to associate with a subset of highly transcribed genes tending to have longer mRNAs rather than shorter, and is also at a significant subset of loci containing the Histone H3K36me3. GLYR1 is expressed at high levels in most tissue types, including stem cells, and has been found to be overexpressed in breast cancer. GLYR1 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
    Purification
    Affinity Purified
    Immunogen
    This antibody was raised against a peptide within the C-terminal region of human GLYR1.
    Isotype
    IgG
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  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Purified IgG in 70 mM Tris, 105 mM NaCl, 0.07 mM EDTA, 31 mM glycine, 30 % glycerol, and 0.035 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
  • Target
    GLYR1 (Glyoxylate Reductase 1 Homolog (GLYR1))
    Alternative Name
    GLYR1 (GLYR1 Products)
    Synonyms
    N-PAC antibody, BM045 antibody, HIBDL antibody, NP60 antibody, 2810419J22Rik antibody, 3930401K13Rik antibody, AW545332 antibody, Npac antibody, 3930401k13rik antibody, N-pac antibody, RGD1309459 antibody, glyoxylate reductase 1 homolog antibody, glyoxylate reductase 1 homolog (Arabidopsis) antibody, GLYR1 antibody, Glyr1 antibody
    Molecular Weight
    65 kDa
    NCBI Accession
    NP_115958
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