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- Target See all CoREST (RCOR1) Antibodies
- CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CoREST antibody is un-conjugated
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Application
- Western Blotting (WB)
- Characteristics
- CoREST (REST corepressor 1, RCOR1) is a corepressor protein recruited by the REST, a neuronal gene-specific transcriptional repressor, to help repress neuron specific gene expression in non-neuronal cell lineages. CoREST is an essential component of the BHC repressor complex that also contains HDAC1, HDAC2, HMG20B/BRAF35, LSD1 (a lysine-4 specific histone demethylase) and PHF21A/BHC80. The Herpes Simplex virus ICP0 protein blocks the repression of viral genes by disrupting the interaction between CoREST and HDAC1/2. CoREST antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.
- Purification
- Affinity Purified
- Immunogen
- This CoREST antibody was raised against a synthetic peptide derived from the C-terminal region of human CoREST.
- Isotype
- IgG
- Top Product
- Discover our top product RCOR1 Primary Antibody
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anti-REST Corepressor 1 (RCOR1) antibody
RCOR1 Reactivity: Human WB, IHC, IP, ChIP Host: Rabbit Monoclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 256-485) antibodyRCOR1 Reactivity: Human WB, IP, IF, ChIP Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 Reactivity: Human, Mouse, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 394-482) antibodyRCOR1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 101-130), (N-Term) antibodyRCOR1 Reactivity: Human WB Host: Rabbit Polyclonal RB36780 unconjugated
anti-REST Corepressor 1 (RCOR1) (N-Term) antibodyRCOR1 Reactivity: Human, Mouse, Monkey, Pig WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (AA 109-293) antibodyRCOR1 Reactivity: Human, Mouse, Rat WB, IHC, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) antibodyRCOR1 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (C-Term) antibodyRCOR1 Reactivity: Human, Mouse, Dog, Guinea Pig, Cow, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-REST Corepressor 1 (RCOR1) (Middle Region) antibodyRCOR1 Reactivity: Human, Mouse, Dog, Guinea Pig, Rat, Cow, Horse WB, IHC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Target
- CoREST (RCOR1) (REST Corepressor 1 (RCOR1))
- Alternative Name
- CoREST (RCOR1 Products)
- Molecular Weight
- 66 kDa
- NCBI Accession
- NP_055971
- Pathways
- Regulation of Hormone Metabolic Process, Chromatin Binding
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