BRD3 antibody (C-Term)

Catalog No. ABIN6971459

Product Details anti-BRD3 Antibody

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Binding Specificity: C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD3 antibody is un-conjugated

Application: Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq), Chromatin Immunoprecipitation (ChIP), Cleavage Under Targets and Release Using Nuclease (CUT&RUN)

Characteristics: BRD3 (Bromodomain Containing 3) is a member of the mammalian BET (Bromodomain Extra Terminal) family of proteins, binds hyperacetylated chromatin and has been reported to interact with acetylated Histone H4K5, Histone H4K12 and Histone H3K14. It plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene. BRD3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Chromatin Immunoprecipitation, ChIP-Seq and Western blot, it has been shown to react with Human and Mouse samples.

Purification: Affinity Purified

Immunogen: This antibody was raised against a peptide within the C-terminal region of mouse BRD3.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for BRD3

Target: BRD3 (Bromodomain Containing 3 (BRD3))

Alternative Name: BRD3 (BRD3 Products)

Synonyms: ORFX antibody, RING3L antibody, 2410084F24Rik antibody, AW060456 antibody, Fsrg2 antibody, RINGL3 antibody, brd3 antibody, fi36b10 antibody, wu:fa13h06 antibody, wu:fc01d09 antibody, wu:fc74a08 antibody, wu:fi04h10 antibody, wu:fi36b10 antibody, BRD3 antibody, ring3l antibody, fa28f05 antibody, wu:fa28f05 antibody, wu:fc56a11 antibody, wu:fj66d12 antibody, zgc:77289 antibody, bromodomain containing 3 antibody, bromodomain containing 3a antibody, bromodomain containing 3 S homeolog antibody, bromodomain-containing protein 3 antibody, bromodomain containing 3b antibody, BRD3 antibody, Brd3 antibody, brd3a antibody, brd3.S antibody, LOC100410652 antibody, LOC100354641 antibody, brd3b antibody

Molecular Weight: 100 kDa

NCBI Accession: NP_001107046

Pathways: Chromatin Binding