IL-12/IL-23 p40 antibody
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- Target See all IL-12/IL-23 p40 products
- IL-12/IL-23 p40
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Reactivity
- Mouse
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Host
- Rat
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Clonality
- Monoclonal
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Conjugate
- This IL-12/IL-23 p40 antibody is un-conjugated
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Application
- Neutralization (Neut)
- Specificity
- Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).
- Purification
- Purified from in vitro cultures by protein G affinity chromatography.
- Immunogen
- Recombinant mouse IL-12 p70
- Clone
- C17-8
- Isotype
- IgG2a
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- Application Notes
- Neutralization of mouse IL-12 and IL-23 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- supplied at 1 mg/mL in PBS free of preservatives
- Preservative
- Without preservative
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
- Expiry Date
- 18 months
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Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus." in: Infection and immunity, Vol. 79, Issue 12, pp. 5010-8, (2012) (PubMed).
: "Delayed maturation of an IL-12-producing dendritic cell subset explains the early Th2 bias in neonatal immunity." in: The Journal of experimental medicine, Vol. 205, Issue 10, pp. 2269-80, (2008) (PubMed).
: "Neutralization or absence of the interleukin-23 pathway does not compromise immunity to mycobacterial infection." in: Infection and immunity, Vol. 74, Issue 11, pp. 6092-9, (2006) (PubMed).
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Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus." in: Infection and immunity, Vol. 79, Issue 12, pp. 5010-8, (2012) (PubMed).
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- Target
- IL-12/IL-23 p40
- Alternative Name
- IL12/23 (p40) (IL-12/IL-23 p40 Products)
- Gene ID
- 16160
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