IL-5 antibody

Catalog No. ABIN6964015

Product Details anti-IL-5 Antibody

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-5 antibody is un-conjugated

Application: Neutralization (Neut)

Specificity: Native and recombinant IL-5.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Mouse IL-5

Clone: TRFK5

Isotype: IgG1

Application Details

Application Notes: Neutralization of mouse IL-5 and human IL-5 bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Preservative: Without preservative

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-5 antibody (ABIN6964015)

Stathopoulos, Sherrill, Karabela, Goleniewska, Kalomenidis, Roussos, Fingleton, Yull, Peebles, Blackwell: "Host-derived interleukin-5 promotes adenocarcinoma-induced malignant pleural effusion." in: American journal of respiratory and critical care medicine, Vol. 182, Issue 10, pp. 1273-81, (2010) (PubMed).

McKee, Munks, MacLeod, Fleenor, Van Rooijen, Kappler, Marrack: "Alum induces innate immune responses through macrophage and mast cell sensors, but these sensors are not required for alum to act as an adjuvant for specific immunity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 7, pp. 4403-14, (2009) (PubMed).

Eum, Hailé, Lefort, Huerre, Vargaftig: "Eosinophil recruitment into the respiratory epithelium following antigenic challenge in hyper-IgE mice is accompanied by interleukin 5-dependent bronchial hyperresponsiveness." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 92, Issue 26, pp. 12290-4, (1996) (PubMed).

Target Details for IL-5

Target: IL-5 (IL5) (Interleukin 5 (IL5))

Alternative Name: IL5 (IL5 Products)

Gene ID: 16191

Pathways: JAK-STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour