TXN antibody (Biotin)

Catalog No. ABIN6963928

Product Details anti-TXN Antibody (Biotin)

Target: TXN (Thioredoxin (TXN))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TXN antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA

Specificity: Native and recombinant Thioredoxin-1

Cross-Reactivity (Details): The antibody cross-reacts with Trx1 from cow. For quantification of human Trx1 in ELISA, samples should not contain bovine serum.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human Thioredoxin-1

Clone: MT13X3

Isotype: IgG1

Application Details

Application Notes: For quantification of Trx1 in solution e.g. cell culture supernatants and serum/ plasma using ELISA. MT13X3 is recommended as detection mAb in combination with coating mAb MT17R6 . MT13X3 is also suitable for Western blot.

Comment:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-TXN antibody (Biotin) (ABIN6963928)

Faghih, Rostami-Nejad, Amani, Sadeghi, Pourhoseingholi, Masotti, Zali: "Analysis of IL17A and IL21 Expression in the Small Intestine of Celiac Disease Patients and Correlation with Circulating Thioredoxin Level." in: Genetic testing and molecular biomarkers, Vol. 22, Issue 9, pp. 518-525, (2018) (PubMed).

Mahmoudian, Khalilnezhad, Gharagozli, Amani et al.: "Thioredoxin-1, redox factor-1 and thioredoxin-interacting protein, mRNAs are differentially expressed in Multiple Sclerosis patients exposed and non-exposed to interferon and immunosuppressive ..." in: Gene, Vol. 634, pp. 29-36, (2017) (PubMed).

Reiser, Mathys, Curbo, Pannecouque, Noppen, Liekens, Engman, Lundberg, Balzarini, Karlsson: "The Cellular Thioredoxin-1/Thioredoxin Reductase-1 Driven Oxidoreduction Represents a Chemotherapeutic Target for HIV-1 Entry Inhibition." in: PLoS ONE, Vol. 11, Issue 1, pp. e0147773, (2016) (PubMed).

Lundberg, Curbo, Reiser, Masterman, Braesch-Andersen, Areström, Ahlborg: "Methodological aspects of ELISA analysis of thioredoxin 1 in human plasma and cerebrospinal fluid." in: PLoS ONE, Vol. 9, Issue 7, pp. e103554, (2015) (PubMed).

Target Details for TXN

Target: TXN (Thioredoxin (TXN))

Alternative Name: Thioredoxin1 (TXN Products)

Synonyms: TRDX antibody, TRX antibody, TRX1 antibody, ADF antibody, AW550880 antibody, Trx1 antibody, Txn antibody, trx antibody, TXN antibody, SCM1.18 antibody, trxA3 antibody, thioredoxin antibody, TR-1 antibody, Trx-1 antibody, thioredoxin antibody, thioredoxin 1 antibody, thioredoxin L homeolog antibody, similar to 44RRORF109c hypothetical protein; similar to bacterial thioredoxin (SwissProt P06544) antibody, thioredoxin pseudogene antibody, cytosolic thioredoxin Trx1 antibody, TXN antibody, Txn1 antibody, txn.L antibody, txn antibody, trx antibody, SCO0885 antibody, PHG25ORF099c antibody, LOC100349046 antibody, Txn antibody, trx1 antibody

Gene ID: 7295

Pathways: Carbohydrate Homeostasis, Cell RedoxHomeostasis