IL23 antibody (Biotin)

Catalog No. ABIN6963867

Product Details anti-IL23 Antibody (Biotin)

Target: IL23 (Interleukin 23 (IL23))

Reactivity: Human, Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL23 antibody is conjugated to Biotin

Application: ELISA, ELISpot

Specificity: Native and recombinant IL-23. The antibody recognizes the p19 subunit of the IL-23 heterodimer (p40+p19).

Cross-Reactivity (Details): The monoclonal antibody cross-reacts with IL-23 from non-human primates.

Characteristics: This monoclonal antibody enables specific detection of human IL-23 in immunoassays such as ELISpot and ELISA. Serum/Plasma samples

Purification: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human IL-23

Clone: MT155

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

ABIN6963867, ABIN7448310 and ABIN6964023 is recommended as detection mAb in ELISpot and ELISA in combination with capture mAbs .

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL23 antibody (Biotin) (ABIN6963867)

Apatzidou, Iskas, Konstantinidis, Alghamdi, Tumelty, Lappin, Nile: "Clinical associations between acetylcholine levels and cholinesterase activity in saliva and gingival crevicular fluid and periodontal diseases." in: Journal of clinical periodontology, Vol. 45, Issue 10, pp. 1173-1183, (2019) (PubMed).

Tagawa, Albanese, Bouvet, Moosmann, Mautner, Heissmeyer, Zielinski, Lutter, Hoser, Hastreiter, Hayes, Sugden, Hammerschmidt: "Epstein-Barr viral miRNAs inhibit antiviral CD4+ T cell responses targeting IL-12 and peptide processing." in: The Journal of experimental medicine, Vol. 213, Issue 10, pp. 2065-80, (2017) (PubMed).

Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." in: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

Warfel, Merkel: "Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates." in: Mucosal immunology, Vol. 6, Issue 4, pp. 787-96, (2014) (PubMed).

Target Details for IL23

Target: IL23 (Interleukin 23 (IL23))

Alternative Name: IL23 (IL23 Products)

Synonyms: IL-23 antibody, p19 antibody, SGRF antibody, il23p19 antibody, interleukin 23, alpha subunit p19 antibody, interleukin 23 subunit alpha antibody, Il23a antibody, IL23A antibody

Gene ID: 51561