IL-12/IL-23 p40 antibody (Biotin)

Catalog No. ABIN6963863

Product Details anti-IL-12/IL-23 p40 Antibody (Biotin)

Target: IL-12/IL-23 p40

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-12/IL-23 p40 antibody is conjugated to Biotin

Application: ELISA, ELISpot

Specificity: Native and recombinant p40 subunit of mouse IL-12 and IL-23. The antibody recognizes p40 monomer, p40 homodimer, IL-12 p70 heterodimer (p40+p35) and IL-23 heterodimer (p40+p19).

Purification: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse IL-12 p70

Clone: C17-8

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-12/IL-23 p40 antibody (Biotin) (ABIN6963863)

Bain, Oliphant, Thomson, Kullberg, Mowat: "Proinflammatory Role of Monocyte-Derived CX3CR1int Macrophages in Helicobacter hepaticus-Induced Colitis." in: Infection and immunity, Vol. 86, Issue 2, (2018) (PubMed).

Quast, Keller, Weber, Schneider, von Gunten, Lünemann: "Protection from experimental autoimmune encephalomyelitis by polyclonal IgG requires adjuvant-induced inflammation." in: Journal of neuroinflammation, Vol. 13, pp. 42, (2016) (PubMed).

Rahman, Chuquimia, Petursdottir, Periolo, Singh, Fernández: "Impact of toll-like receptor 2 deficiency on immune responses to mycobacterial antigens." in: Infection and immunity, Vol. 79, Issue 11, pp. 4649-56, (2011) (PubMed).

Pavlenko, Leder, Moreno, Levitsky, Pisa: "Priming of CD8+ T-cell responses after DNA immunization is impaired in TLR9- and MyD88-deficient mice." in: Vaccine, Vol. 25, Issue 34, pp. 6341-7, (2007) (PubMed).

Target Details for IL-12/IL-23 p40

Target: IL-12/IL-23 p40

Alternative Name: IL12/23 (p40) (IL-12/IL-23 p40 Products)

Gene ID: 16160