ITGA2 antibody (Biotin)

Catalog No. ABIN7278105

Product Details anti-ITGA2 Antibody (Biotin)

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Reactivity: Mouse

Host: Armenian Hamster

Clonality: Monoclonal

Conjugate: This ITGA2 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Purification: This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

Clone: HMa2

Isotype: IgG

Application Details

Application Notes: This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indicated). Please refer to the figure legend for the optimal concentration used to stain the tissue shown. We recommend titrating the antibody under your specific conditions to determine the optimal concentration of antibody needed in your experimental system.

Comment:

0.5 mg/mL

Restrictions: For Research Use only

Handling

Buffer: 10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C protected from light

Expiry Date: 12 months

Target Details for ITGA2

Target: ITGA2 (Integrin alpha 2 (ITGA2))

Alternative Name: CD49b (ITGA2 Products)

Synonyms: BR antibody, CD49B antibody, GPIa antibody, HPA-5 antibody, VLA-2 antibody, VLAA2 antibody, DX5 antibody, integrin subunit alpha 2 antibody, integrin alpha 2 antibody, ITGA2 antibody, Itga2 antibody

Background: The HMa2 antibody reacts with mouse CD49b, a 150 kDa glycoprotein member of the integrin family. CD49b, also known as integrin alpha2, associates non- covalently with CD29 (integrin beta1) to form the VLA-2 heterodimer. VLA-2 integrins function as cellular receptors for collagen and laminin. CD49b is expressed by platelets, intestinal epithelial cells, NK cells, epithelial cells, and a subset of CD4+ T cells. CD49b plays an essential role in mediating the adhesion of cells to the extracellular matrix.

Gene ID: 16398

UniProt: Q62469

Pathways: CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Integrin Complex