This SARS-CoV-2 Nucleocapsid antibody is un-conjugated
Application
ELISA, SDS-PAGE (SDS)
Purpose
Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1
Characteristics
Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 (ABIN6953177) is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293).
Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4 . Normally trehalose is added as protectant before lyophilization.
Handling Advice
Please avoid repeated freeze-thaw cycles.
Storage
4 °C,-20 °C,-80 °C
Storage Comment
For long term storage, the product should be stored at lyophilized state at -20°C or lower. This product is stable after storage at: 4-8°C for 12 months in lyophilized state, -70°C for 3 years under sterile conditions after reconstitution.
Nucleocapsid protein is a most abundant protein of coronavirus. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. While screening for ADP-ribosylated proteins during coronavirus (CoV) infection, we identified as the viral nucleocapsid (N) protein. Novel post-translation modification of the CoV N protein that may play a regulatory role for this important structural protein. The array of diverse functional activities accommodated in the hantaviral N protein goes far beyond to be a static structural protein and makes it an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.