MLL1 antibody

Catalog No. ABIN6952424

Product Details anti-MLL1 Antibody

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MLL1 antibody is un-conjugated

Application: Chromatin Immunoprecipitation (ChIP), ELISA, ChIP DNA-Sequencing (ChIP-seq)

Specificity: Polyclonal antibody raised in rabbit against human MLL1 (Mixed-Lineage Leukemia) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.

Purification: whole antiserum

Grade: ChIP-seq Grade

Immunogen: synthetic peptide

Application Details

Application Notes: ChIP/ChIP-seq 2 μL:ChIP
ELISA 1:100 - 1:1,000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: serum, 0.05 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for MLL1

Target: MLL1 (Myeloid/lymphoid Or Mixed-Lineage Leukemia 1 (MLL1))

Alternative Name: MLL1 (MLL1 Products)

Synonyms: Mll antibody, Mll1 antibody, 6430520K01 antibody, ALL-1 antibody, All1 antibody, Cxxc7 antibody, HRX antibody, HTRX1 antibody, mKIAA4050 antibody, lysine methyltransferase 2A antibody, lysine (K)-specific methyltransferase 2A antibody, Kmt2a antibody

Background: MLL1 (UniProtKB/Swiss-Prot entry Q03164) functions as a lysine methyltransferase responsible for the methylation of H3K4 which is associated with epigenetic transcriptional activation. MLL1 regulates the transcription of specific target genes, including many of the HOX genes and plays an essential role in regulating gene expression during early development and hematopoiesis. It also plays a role in the control of circadian gene expression. Mll1 is involved in several translocations which cause certain acute lymphoid leukemias and acute myeloid leukemias.

UniProt: Q03164