VPS45 antibody (AA 401-500)

Catalog No. ABIN6945342

Product Details anti-VPS45 Antibody

Target: VPS45 (Vacuolar Protein Sorting 45 (VPS45))

Binding Specificity: AA 401-500

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS45 antibody is un-conjugated

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VPS45A

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for VPS45

Target: VPS45 (Vacuolar Protein Sorting 45 (VPS45))

Alternative Name: VPS45A (VPS45 Products)

Background:

Synonyms: h-VPS45, H1, H1VPS45, HGNC:14579, hlVps45, Leucocyte vacuolar protein sorting 45, OTTHUMP00000014482, Vacuolar protein sorting 45 homolog (S. cerevisiae), Vacuolar protein sorting 45A (yeast homolog), Vacuolar protein sorting 45A, Vacuolar protein sorting 45B (yeast), Vacuolar protein sorting-associated protein 45, VPS45, VPS45_HUMAN, VPS45A, VPS45B, VPS54A, VSP45, VSP45A.

Background: Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]

Gene ID: 11311

UniProt: Q9NRW7

Pathways: Transition Metal Ion Homeostasis, Synaptic Vesicle Exocytosis