TNP1 antibody (AA 201-300)

Catalog No. ABIN6945217

Product Details anti-TNP1 Antibody

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Binding Specificity: AA 201-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TNP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse Transition Protein 1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for TNP1

Target: TNP1 (Transition Protein 1 (During Histone To Protamine Replacement) (TNP1))

Alternative Name: Transition Protein 1 (TNP1 Products)

Synonyms: TNP1 antibody, TP1 antibody, Stp-1 antibody, Tp-1 antibody, STP-1 antibody, TP-1 antibody, transition protein 1 antibody, TNP1 antibody, Tnp1 antibody

Background:

Synonyms: 551G9.2, Anti Eukaryotic Release Factor 3a, Anti G1 to S phase transition 1, Anti GST1, homolog of yeast, eRF 3a, eRF3a, G1 to S phase transition 1, G1 to S phase transition protein 1 homolog, G1 to S phase transition protein, GSPT 1, GSPT1, GST 1, GST1, GTP binding protein GST1 HS, Transition protein 1, ERF3A_MOUSE.

Background: eRF3a is a 499 amino acid protein that belongs to the GTP-binding elongation factor family and is involved in the regulation of cell growth, specifically via control of translation termination. Human eRF3a shares 94 % sequence identity with its mouse counterpart, suggesting a conserved function between species. The gene encoding eRF3a maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3 % of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Gene ID: 14852

UniProt: P15170