TMPRSS11D antibody (AA 21-120) (Biotin)

Catalog No. ABIN6945187

Product Details anti-TMPRSS11D Antibody (Biotin)

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS11D antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TMPRSS11D

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TMPRSS11D

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Alternative Name: TMPRSS11D (TMPRSS11D Products)

Synonyms: HAT antibody, AST antibody, AsP antibody, BC020151 antibody, Asp antibody, Tmprss11d antibody, transmembrane protease, serine 11D antibody, transmembrane protease, serine 11d antibody, transmembrane protease serine 11D antibody, TMPRSS11D antibody, Tmprss11d antibody, LOC100720850 antibody

Background:

Synonyms: Airway trypsin like protease, Airway trypsin-like protease, HAT, MGC150587, MGC150588, TM11D_HUMAN, TMPRSS11D, Transmembrane protease serine 11D, Transmembrane protease serine 11D catalytic chain, Transmembrane protease serine 11D precursor.

Background: This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. [provided by RefSeq, Jul 2008]

Gene ID: 9407

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process