TACC3 antibody

Catalog No. ABIN6945113

Product Details anti-TACC3 Antibody

Target: TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TACC3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human TACC3 between 50-150 amino acids

Clone: 2F9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TACC3

Target: TACC3 (Transforming, Acidic Coiled-Coil Containing Protein 3 (TACC3))

Alternative Name: TACC3 (TACC3 Products)

Synonyms: Aint antibody, C86661 antibody, Eric1 antibody, ERIC-1 antibody, ERIC1 antibody, maskin antibody, masking antibody, xmaskin antibody, transforming, acidic coiled-coil containing protein 3 antibody, transforming acidic coiled-coil containing protein 3 antibody, transforming acidic coiled-coil containing protein 3 S homeolog antibody, Tacc3 antibody, TACC3 antibody, tacc3.S antibody

Background:

Synonyms: Transforming acidic coiled-coil-containing protein 3, ERIC-1, TACC3

Background: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors (By similarity). Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubule bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:21297582, PubMed:23532825). May be involved in the control of cell growth and differentiation. May contribute to cancer (PubMed:14767476).

Gene ID: 10460

UniProt: Q9Y6A5

Pathways: Maintenance of Protein Location