TTC37 antibody
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- Target See all TTC37 Antibodies
- TTC37 (Tetratricopeptide Repeat Domain 37 (TTC37))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TTC37 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunofluorescence (Cultured Cells) (IF (cc))
- Cross-Reactivity
- Human
- Purification
- Protein G purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300
- Immunogen
- Polyclonal antibody raised in rabbit against human SKI3, using a recombinant protein
- Top Product
- Discover our top product TTC37 Primary Antibody
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anti-Tetratricopeptide Repeat Domain 37 (TTC37) antibody
TTC37 Reactivity: Human WB, ChIP, FM Host: Rabbit Polyclonal unconjugated
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- Application Notes
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WB 1:300-5000
IF(ICC) 1:50-200
IF() - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 3 μg/μL
- Buffer
- PBS with 0.05 % sodium azide and 0.05 % Proclin300.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- TTC37 (Tetratricopeptide Repeat Domain 37 (TTC37))
- Alternative Name
- Ski3 (TTC37 Products)
- Synonyms
- KIAA0372 antibody, Ski3 antibody, tetratricopeptide repeat domain 37 antibody, tetratricopeptide repeat domain 37 L homeolog antibody, TTC37 antibody, ttc37.L antibody
- Background
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Synonyms: Antiviral protein SKI8, SKI8, Superkiller protein 8, REC103
Background: Involved in double-strand break (DSB) formation during meiotic recombination through stabilization of SPO11 association with meiotic chromosome and helping SPO11 to recruit other DSB proteins like REC102 and REC104 to meiotic chromosomes. Also component of the SKI complex involved in 3'-mRNA degradation pathway. Represses dsRNA virus propagation by specifically blocking translation of viral mRNAs, perhaps recognizing the absence of CAP or poly(A). Essential for controlling the propagation of M double-stranded RNA (dsRNA) and thus for preventing virus-induced cytopathology.
- Gene ID
- 852659
- UniProt
- Q02793
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