SCFD2 antibody (AA 501-600) (Biotin)

Catalog No. ABIN6944828

Product Details anti-SCFD2 Antibody (Biotin)

Target: SCFD2 (Sec1 Family Domain Containing 2 (SCFD2))

Binding Specificity: AA 501-600

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SCFD2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SCFD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SCFD2

Target: SCFD2 (Sec1 Family Domain Containing 2 (SCFD2))

Alternative Name: SCFD2 (SCFD2 Products)

Synonyms: STXBP1L1 antibody, 9330137G15 antibody, E430013M20Rik antibody, sec1 family domain containing 2 antibody, Sec1 family domain containing 2 antibody, Scfd2 antibody, SCFD2 antibody

Background:

Synonyms: FLJ21060, FLJ39514, SCFD 2, Scfd2, SCFD2_HUMAN, Sec1 family domain containing 2, Sec1 family domain containing protein 2, Sec1 family domain-containing protein 2, STXBP1L1, Syntaxin binding protein 1 like 1, Syntaxin-binding protein 1-like 1.

Background: SCFD2 is a 684 amino acid protein suggested to play a role in protein transport. Existing as two alternatively spliced isoforms, SCFD2 is a member of the STXBP/unc-18/SEC1 family and is encoded by a gene that maps to human chromosome 4q12. Chromosome 4 represents approximately 6 % of the human genome and contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

Gene ID: 152579

UniProt: Q8WU76