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PCK1 antibody

PCK1 Reactivity: Human IHC (p), IF (cc), IF (p), FACS Host: Rabbit Monoclonal 6C1 unconjugated
Catalog No. ABIN6944451
  • Target See all PCK1 Antibodies
    PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
    Reactivity
    • 79
    • 55
    • 30
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 94
    • 9
    • 2
    • 2
    Rabbit
    Clonality
    • 92
    • 15
    Monoclonal
    Conjugate
    • 48
    • 9
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This PCK1 antibody is un-conjugated
    Application
    • 86
    • 38
    • 28
    • 13
    • 13
    • 12
    • 10
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
    Cross-Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    Synthetic peptide within human PCK1 aa 1-50
    Clone
    6C1
    Isotype
    IgG
    Top Product
    Discover our top product PCK1 Primary Antibody
  • Application Notes
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
    Alternative Name
    PCK1 (PCK1 Products)
    Background

    Synonyms: Phosphoenolpyruvate carboxykinase cytosolic [GTP], phosphoenolpyruvate carboxykinase 1, PEPCK-C, PCK1, PEPCK1.

    Background: Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate.

    Gene ID
    5105
    UniProt
    P35558
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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