PCK1 antibody
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- Target See all PCK1 Antibodies
- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PCK1 antibody is un-conjugated
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Application
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
- Cross-Reactivity
- Human
- Purification
- Purified by Protein A.
- Immunogen
- Synthetic peptide within human PCK1 aa 1-50
- Clone
- 6C1
- Isotype
- IgG
- Top Product
- Discover our top product PCK1 Primary Antibody
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- Application Notes
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FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- PCK1 (phosphoenolpyruvate Carboxykinase 1 (Soluble) (PCK1))
- Alternative Name
- PCK1 (PCK1 Products)
- Background
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Synonyms: Phosphoenolpyruvate carboxykinase cytosolic [GTP], phosphoenolpyruvate carboxykinase 1, PEPCK-C, PCK1, PEPCK1.
Background: Regulates cataplerosis and anaplerosis, the processes that control the levels of metabolic intermediates in the citric acid cycle. At low glucose levels, it catalyzes the cataplerotic conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. At high glucose levels, it catalyzes the anaplerotic conversion of phosphoenolpyruvate to oxaloacetate.
- Gene ID
- 5105
- UniProt
- P35558
- Pathways
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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