NXF1 antibody

Catalog No. ABIN6944348

Product Details anti-NXF1 Antibody

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NXF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within c-terminal human NXF1.

Clone: 1G8

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IF(ICC) 1:50-200
IP(1-2 μg)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for NXF1

Target: NXF1 (Nuclear RNA Export Factor 1 (NXF1))

Alternative Name: NXF1 (NXF1 Products)

Synonyms: im:7156527 antibody, wu:fc12d06 antibody, MGC82224 antibody, NXF1 antibody, tap antibody, mex67 antibody, MEX67 antibody, TAP antibody, Mex67 antibody, Mvb1 antibody, Tap antibody, Mex67h antibody, nuclear RNA export factor 1 antibody, nuclear RNA export factor 1 S homeolog antibody, Nuclear RNA export factor 1 antibody, nxf1 antibody, nxf1.S antibody, NXF1 antibody, LOC100113601 antibody, Tsp_03999 antibody, Nxf1 antibody, nxf-1 antibody

Background:

Synonyms: Nuclear RNA export factor 1, Tip-associated protein, Tip-associating protein, mRNA export factor TAP, NXF1, MEX67, TAP

Background: Involved in the nuclear export of mRNA species bearing retroviral constitutive transport elements (CTE) and in the export of mRNA from the nucleus to the cytoplasm (TAP/NFX1 pathway). The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5 components of the TREX complex. ALYREF/THOC4-bound mRNA is thought to be transferred to the NXF1-NXT1 heterodimer for export. Also involved in nuclear export of m6A-containing mRNAs: interaction between SRSF3 and YTHDC1 facilitates m6A-containing mRNA-binding to both SRSF3 and NXF1, promoting mRNA nuclear export.

Gene ID: 10482

UniProt: Q9UBU9