MDFI antibody (AA 101-200) (AbBy Fluor® 750)
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- Target See all MDFI Antibodies
- MDFI (MyoD Family Inhibitor (MDFI))
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Binding Specificity
- AA 101-200
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This MDFI antibody is conjugated to AbBy Fluor® 750
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificity
- In Mice, there is possible cross-reactivity with Glycoprotein endo-alpha-1,2-mannosidase (67 % homology with immunogen sequence, 53 kDa)
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Cow,Sheep,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human MDFI
- Isotype
- IgG
- Top Product
- Discover our top product MDFI Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- MDFI (MyoD Family Inhibitor (MDFI))
- Alternative Name
- MDFI (MDFI Products)
- Synonyms
- MDFI antibody, I-MF antibody, I-mfa antibody, I-mf antibody, RGD1560271 antibody, MyoD family inhibitor antibody, MDFI antibody, Mdfi antibody
- Background
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Synonyms: I MF, I mfa, Inhibitor of MyoD family a, Mdfi, MDFI_HUMAN, MyoD family inhibitor, Myogenic repressor I-mf, OTTHUMP00000016375, OTTHUMP00000016376, OTTHUMP00000196103, OTTHUMP00000196414, OTTHUMP00000196415.
Background: Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways (By similarity).
- Gene ID
- 4188
- UniProt
- Q99750
- Pathways
- Maintenance of Protein Location
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